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Under denna rubrik finns forskning om Hjärnan i samband med olika yogiska aktiviteter Sammandragen ligger i kronologisk ordning.
F.n. finns totalt 24 sammandrag ur olika forskningsrapporter under rubriken ”Hjärnan”
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Non-linear dynamic complexity of the human EEG during meditation.
Aftanas LI, Golocheikine SA.
Psychophysiology Laboratory, State-Research Institute of Physiology, Siberian Branch, Russian Academy of Medical Sciences, Timakova str. 4, 630117, Novosibirsk, Russia. aftanas@iph.ma.nsc.ru
We used non-linear analysis to investigate the dynamical properties underlying the EEG in the model of Sahaja Yoga meditation. Non-linear dimensional complexity (DCx) estimates, indicating complexity of neuronal computations, were analyzed in 20 experienced meditators during rest and meditation using 62-channel EEG. When compared to rest, the meditation was accompanied by a focused decrease of DCx estimates over midline frontal and central regions. By contrast, additionally computed linear measures exhibited the opposite direction of changes: power in the theta-1 (4-6 Hz), theta-2 (6-8 Hz) and alpha-1 (8-10 Hz) frequency bands was increased over these regions. The DCx estimates negatively correlated with theta-2 and alpha-1 and positively with beta-3 (22-30 Hz) band power. It is suggested that meditative experience, characterized by less complex dynamics of the EEG, involves 'switching off' irrelevant networks for the maintenance of focused internalized attention and inhibition of inappropriate information. Overall, the results point to the idea that dynamically changing inner experience during meditation is better indexed by a combination of non-linear and linear EEG variables.
Aftanas LI, Golocheikine SA.
Psychophysiology Laboratory, State-
We used non-
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Brain Res Cogn Brain Res 2002 Apr;13(2):255-9
Increased dopamine tone during meditation-induced change of consciousness.
Kjaer TW, Bertelsen C, Piccini P, Brooks D, Alving J, Lou HC.
John F. Kennedy Institute, Gl. Landevej 7, 2600, Glostrup, Denmark
This is the first in vivo demonstration of an association between endogenous neurotransmitter release and conscious experience. Using 11C-raclopride PET we demonstrated increased endogenous dopamine release in the ventral striatum during Yoga Nidra meditation. Yoga Nidra is characterized by a depressed level of desire for action, associated with decreased blood flow in prefrontal, cerebellar and subcortical regions, structures thought to be organized in open loops subserving executive control. In the striatum, dopamine modulates excitatory glutamatergic synapses of the projections from the frontal cortex to striatal neurons, which in turn project back to the frontal cortex via the pallidum and ventral thalamus. The present study was designed to investigate whether endogenous dopamine release increases during loss of executive control in meditation. Participants underwent two 11C-raclopride PET scans: one while attending to speech with eyes closed, and one during active meditation. The tracer competes with endogenous dopamine for access to dopamine D2 receptors predominantly found in the basal ganglia. During meditation, 11C-raclopride binding in ventral striatum decreased by 7.9%. This corresponds to a 65% increase in endogenous dopamine release. The reduced raclopride binding correlated significantly with a concomitant increase in EEG theta activity, a characteristic feature of meditation. All participants reported a decreased desire for action during meditation, along with heightened sensory imagery. The level of gratification and the depth of relaxation did not differ between the attention and meditation conditions. Here we show increased striatal dopamine release during meditation associated with the experience of reduced readiness for action. It is suggested that being in the conscious state of meditation causes a suppression of cortico-striatal glutamatergic transmission. To our knowledge this is the first time in vivo evidence has been provided for regulation of conscious states at a synaptic level.
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Kjaer TW, Bertelsen C, Piccini P, Brooks D, Alving J, Lou HC.
John F. Kennedy Institute, Gl. Landevej 7, 2600, Glostrup, Denmark
This is the first in vivo demonstration of an association between endogenous neurotransmitter release and conscious experience. Using 11C-
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Seizure 2001 Jan;10(1):3-6
Yoga for epilepsy: methodological issues.
Ramaratnam S.
Apollo Hospital, Madras, 600006, India. rsridharan@vsnl.com
This article deals with the methodological issues that might be encountered in designing and conducting a randomized controlled study of the efficacy of yoga in the treatment of epilepsy. Methodological issues relating to patient selection, randomization, blinding, type of intervention, outcome measures and analysis are highlighted. Copyright 2001 BEA Trading Ltd.
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Ramaratnam S.
Apollo Hospital, Madras, 600006, India. rsridharan@vsnl.com
This article deals with the methodological issues that might be encountered in designing and conducting a randomized controlled study of the efficacy of yoga in the treatment of epilepsy. Methodological issues relating to patient selection, randomization, blinding, type of intervention, outcome measures and analysis are highlighted. Copyright 2001 BEA Trading Ltd.
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Seizure 2001 Jan;10(1):7-12
Yoga for control of epilepsy.
Yardi N.
Yardi Epilepsy Clinic, Kothrud, Pune, India. nyardi@hotmail.com
Yoga is an age-old traditional Indian psycho-philosophical-cultural method of leading one's life, that alleviates stress, induces relaxation and provides multiple health benefits to the person following its system. It is a method of controlling the mind through the union of an individual's dormant energy with the universal energy. Commonly practiced yoga methods are 'Pranayama' (controlled deep breathing), 'Asanas' (physical postures) and 'Dhyana' (meditation) admixed in varying proportions with differing philosophic ideas. A review of yoga in relation to epilepsy encompasses not only seizure control but also many factors dealing with overall quality-of-life issues (QOL). This paper reviews articles related to yoga and epilepsy, seizures, EEG, autonomic changes, neuro-psychology, limbic system, arousal, sleep, brain plasticity, motor performance, brain imaging studies, and rehabilitation. There is a dearth of randomized, blinded, controlled studies related to yoga and seizure control. A multi-centre, cross-cultural, preferably blinded (difficult for yoga), well-randomized controlled trial, especially using a single yogic technique in a homogeneous population such as Juvenile myoclonic epilepsy is justified to find out how yoga affects seizure control and QOL of the person with epilepsy. Copyright 2001 BEA Trading Ltd.
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Yardi N.
Yardi Epilepsy Clinic, Kothrud, Pune, India. nyardi@hotmail.com
Yoga is an age-
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Percept Mot Skills 2000 Jun;90(3 Pt 1):1027-32
Decrease in serum cortisol during yoga exercise is correlated with alpha wave activation.
Kamei T, Toriumi Y, Kimura H, Ohno S, Kumano H, Kimura K.
Shimane Institute of Health Science, Izumo, Japan.
We examined changes in brain waves and blood levels of serum cortisol during yoga exercise in 7 yoga instructors and found that alpha waves increased and serum cortisol decreased. These two measures were negatively correlated (r = -.83). Comparison with a control group of nonpractitioners is desirable.
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Kamei T, Toriumi Y, Kimura H, Ohno S, Kumano H, Kimura K.
Shimane Institute of Health Science, Izumo, Japan.
We examined changes in brain waves and blood levels of serum cortisol during yoga exercise in 7 yoga instructors and found that alpha waves increased and serum cortisol decreased. These two measures were negatively correlated (r = -
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Indian J Physiol Pharmacol 2000 Apr;44(2):197-201
Effect of yoga training on maze learning.
Telles S, Ramaprabhu V, Reddy SK.
Vivekananda Kendra Yoga Research Foundation, Appajappa Agrahara.
The performance in a maze learning task was assessed in adults of either sex (n = 31) before and after 30 days of yoga training and in an age and gender matched control group of subjects who did not receive training in yoga. Subjects were blind folded and used the dominant hand to trace the path in a wooden pencil maze. At each assessment, subjects were given 5 trials, without a gap between them. Performance was based on the time taken to complete the maze and the number of blind alleys taken. The time and error scores of Trial 1 were significantly less after yoga (two-factor ANOVA, Tukey test). Repeating trials significantly decreased time scores at Trial 5 versus Trial 1, for both groups on Day 1 and for the control group on Day 30. Hence the yoga group showed improved performance in maze tracing at retest 30 days later, which may be related to this group being faster learners and also the effect of yoga itself. Yoga training did not influence maze learning, based on the performance in 5 repeat trials.
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Telles S, Ramaprabhu V, Reddy SK.
Vivekananda Kendra Yoga Research Foundation, Appajappa Agrahara.
The performance in a maze learning task was assessed in adults of either sex (n = 31) before and after 30 days of yoga training and in an age and gender matched control group of subjects who did not receive training in yoga. Subjects were blind folded and used the dominant hand to trace the path in a wooden pencil maze. At each assessment, subjects were given 5 trials, without a gap between them. Performance was based on the time taken to complete the maze and the number of blind alleys taken. The time and error scores of Trial 1 were significantly less after yoga (two-
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Appl Psychophysiol Biofeedback 2000 Mar;25(1):1-12
Effect of Sahaja yoga meditation on auditory evoked potentials (AEP) and visual contrast sensitivity (VCS) in epileptics.
Panjwani U, Selvamurthy W, Singh SH, Gupta HL, Mukhopadhyay S, Thakur L.
Defence Institute of Physiology and Allied Sciences, Delhi, India.
The effect of Sahaja yoga meditation on 32 patients with primary idiopathic epilepsy on regular and maintained antiepileptic medication was studied. The patients were randomly divided into 3 groups: group I practiced Sahaja Yoga meditation twice daily for 6 months under proper guidance; group II practiced postural exercises mimicking the meditation for the same duration; and group III was the control group. Visual Contrast Sensitivity (VCS), Auditory Evoked Potentials (AEP), Brainstem Auditory Evoked Potentials (BAEP), and Mid Latency Responses (MLR) were recorded initially (0 month) and at 3 and 6 months for each group. There was a significant improvement in VCS following meditation practice in group I participants. Na, the first prominent negative peak of MLR and Pa, the positive peak following Na did not register changes in latency. The Na-Pa amplitude of MLR also showed a significant increase. There were no significant changes in the absolute and interpeak latencies of BAEP. The reduced level of stress following meditation practice may make patients more responsive to specific stimuli. Sahaja Yoga meditation appears to bring about changes in some of the electrophysiological responses studied in epileptic patients.
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Panjwani U, Selvamurthy W, Singh SH, Gupta HL, Mukhopadhyay S, Thakur L.
Defence Institute of Physiology and Allied Sciences, Delhi, India.
The effect of Sahaja yoga meditation on 32 patients with primary idiopathic epilepsy on regular and maintained antiepileptic medication was studied. The patients were randomly divided into 3 groups: group I practiced Sahaja Yoga meditation twice daily for 6 months under proper guidance; group II practiced postural exercises mimicking the meditation for the same duration; and group III was the control group. Visual Contrast Sensitivity (VCS), Auditory Evoked Potentials (AEP), Brainstem Auditory Evoked Potentials (BAEP), and Mid Latency Responses (MLR) were recorded initially (0 month) and at 3 and 6 months for each group. There was a significant improvement in VCS following meditation practice in group I participants. Na, the first prominent negative peak of MLR and Pa, the positive peak following Na did not register changes in latency. The Na-
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Cochrane Database Syst Rev 2000;(3):CD001524
Yoga for epilepsy.
Ramaratnam S, Sridharan K.
Department of Neurology, Apollo Hospitals, 21 Greams Lane, Off Greams Road, Madras, Tamil Nadu, India, 600006. rsridharan@vsnl.com
BACKGROUND: Stress is considered an important precipitating factor for seizures. Yoga is believed to induce relaxation and stress reduction. The effect of yoga on the EEG and the autonomic nervous system have been reported. Yoga would be an attractive therapeutic option for epilepsy (if proved effective), in view of its nonpharmacological nature, minimal side effects and international acceptance. OBJECTIVES: To assess the efficacy of yoga in the treatment of patients with epilepsy. SEARCH STRATEGY: We searched the Cochrane Epilepsy Group trial register, the Cochrane Controlled Trials Register (The Cochrane Library Issue 4, 1998), MEDLINE for articles published up to the middle of 1998, and also registries of the research council for complimentary medicine were searched. In addition, we searched the references of all the identified studies. Finally, we contacted the members of the Neurological Society of India, several neurophysiology institutions and yoga institutes to seek any ongoing studies or studies published in nonindexed journals or unpublished studies. SELECTION CRITERIA: Randomized control trials and controlled clinical trials of treatment of epilepsy with yoga. DATA COLLECTION AND ANALYSIS: The data were extracted independently by both reviewers and any discrepancies were resolved by discussion. The main outcomes assessed were percentage of patients rendered seizure free, number of patients with more than 50% reduction in seizure frequency or seizure duration and the overall reduction in seizure frequency. Analyses were on an intention to treat basis. MAIN RESULTS: Only one study met the selection criteria, and recruited a total of 32 patients, 10 to sahaja yoga and 22 to control treatments. Antiepileptic drugs were continued in all. Randomization was by roll of a dice. The results of this study are as follows: (i) Four patients treated with yoga were seizure free for six months compared to none in the control groups. The Odds Ratio (OR) (95% Confidence Interval (CI)) for yoga versus sham yoga group was 14.5 (0.7, 316.7) and for yoga versus no treatment group 17.3 (0.8, 373.5). (ii) Nine patients in the yoga group had more than 50% reduction in seizure frequency compared to only one among the controls. The OR (95% CI) for yoga versus sham yoga group was 81 (4.4, 1504.5) and for the yoga versus no treatment group was 158.3 (5.8, 4335.9). (iii) There was a decline in the average number of attacks per month compared to the baseline frequency among the patients treated with yoga. The weighted mean difference ( 95% CI) between yoga versus sham yoga group was -2.1 (-3.1, -1.0) and for the yoga versus no treatment group -1.1 (-1.8, -0.4). (iv) More than 50% reduction in seizure duration was found in seven of the 10 patients treated with yoga, compared to none among the 22 controls. The OR (95%CI) for yoga versus sham yoga group was 45 (2.0, 1006.8) and for yoga versus no treatment group 53.57 (2.4, 1187.3). REVIEWER'S CONCLUSIONS: No reliable conclusions can be drawn regarding the efficacy of yoga as a treatment for epilepsy. Further studies are necessary to evaluate the efficacy of yoga in the treatment of epilepsy.
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Yoga for epilepsy.
Ramaratnam S, Sridharan K.
Department of Neurology, Apollo Hospitals, 21 Greams Lane, Off Greams Road, Madras, Tamil Nadu, India, 600006. rsridharan@vsnl.com
BACKGROUND: Stress is considered an important precipitating factor for seizures. Yoga is believed to induce relaxation and stress reduction. The effect of yoga on the EEG and the autonomic nervous system have been reported. Yoga would be an attractive therapeutic option for epilepsy (if proved effective), in view of its nonpharmacological nature, minimal side effects and international acceptance. OBJECTIVES: To assess the efficacy of yoga in the treatment of patients with epilepsy. SEARCH STRATEGY: We searched the Cochrane Epilepsy Group trial register, the Cochrane Controlled Trials Register (The Cochrane Library Issue 4, 1998), MEDLINE for articles published up to the middle of 1998, and also registries of the research council for complimentary medicine were searched. In addition, we searched the references of all the identified studies. Finally, we contacted the members of the Neurological Society of India, several neurophysiology institutions and yoga institutes to seek any ongoing studies or studies published in nonindexed journals or unpublished studies. SELECTION CRITERIA: Randomized control trials and controlled clinical trials of treatment of epilepsy with yoga. DATA COLLECTION AND ANALYSIS: The data were extracted independently by both reviewers and any discrepancies were resolved by discussion. The main outcomes assessed were percentage of patients rendered seizure free, number of patients with more than 50% reduction in seizure frequency or seizure duration and the overall reduction in seizure frequency. Analyses were on an intention to treat basis. MAIN RESULTS: Only one study met the selection criteria, and recruited a total of 32 patients, 10 to sahaja yoga and 22 to control treatments. Antiepileptic drugs were continued in all. Randomization was by roll of a dice. The results of this study are as follows: (i) Four patients treated with yoga were seizure free for six months compared to none in the control groups. The Odds Ratio (OR) (95% Confidence Interval (CI)) for yoga versus sham yoga group was 14.5 (0.7, 316.7) and for yoga versus no treatment group 17.3 (0.8, 373.5). (ii) Nine patients in the yoga group had more than 50% reduction in seizure frequency compared to only one among the controls. The OR (95% CI) for yoga versus sham yoga group was 81 (4.4, 1504.5) and for the yoga versus no treatment group was 158.3 (5.8, 4335.9). (iii) There was a decline in the average number of attacks per month compared to the baseline frequency among the patients treated with yoga. The weighted mean difference ( 95% CI) between yoga versus sham yoga group was -
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Cochrane Database Syst Rev 2000;(2):CD001524
Yoga for epilepsy.
Ramaratnam S, Sridharan K.
Department of Neurology, Apollo Hospitals, 21 Greams Lane, Off Greams Road, Madras, Tamil Nadu, India, 600006. rsridharan@vsnl.com
BACKGROUND: Stress is considered an important precipitating factor for seizures. Yoga is believed to induce relaxation and stress reduction. The effect of yoga on the EEG and the autonomic nervous system have been reported. Yoga would be an attractive therapeutic option for epilepsy (if proved effective), in view of its nonpharmacological nature, minimal side effects and international acceptance. OBJECTIVES: To assess the efficacy of yoga in the treatment of patients with epilepsy. SEARCH STRATEGY: We searched the Cochrane Epilepsy Group trial register, the Cochrane Controlled Trials Register (The Cochrane Library Issue 4, 1998), MEDLINE for articles published up to the middle of 1998, and also registries of the research council for complimentary medicine were searched. In addition, we searched the references of all the identified studies. Finally, we contacted the members of the Neurological Society of India, several neurophysiology institutions and yoga institutes to seek any ongoing studies or studies published in nonindexed journals or unpublished studies. SELECTION CRITERIA: Randomized control trials and controlled clinical trials of treatment of epilepsy with yoga. DATA COLLECTION AND ANALYSIS: The data were extracted independently by both reviewers and any discrepancies were resolved by discussion. The main outcomes assessed were percentage of patients rendered seizure free, number of patients with more than 50% reduction in seizure frequency or seizure duration and the overall reduction in seizure frequency. Analyses were on an intention to treat basis. MAIN RESULTS: Only one study met the selection criteria, and recruited a total of 32 patients, 10 to sahaja yoga and 22 to control treatments. Antiepileptic drugs were continued in all. Randomization was by roll of a dice. The results of this study are as follows: (i) Four patients treated with yoga were seizure free for six months compared to none in the control groups. The Odds Ratio (OR) (95% Confidence Interval (CI)) for yoga versus sham yoga group was 14.5 (0.7, 316.7) and for yoga versus no treatment group 17.3 (0.8, 373.5). (ii) Nine patients in the yoga group had more than 50% reduction in seizure frequency compared to only one among the controls. The OR (95% CI) for yoga versus sham yoga group was 81 (4.4, 1504.5) and for the yoga versus no treatment group was 158.3 (5.8, 4335.9). (iii) There was a decline in the average number of attacks per month compared to the baseline frequency among the patients treated with yoga. The weighted mean difference ( 95% CI) between yoga versus sham yoga group was -2.1 (-3.1, -1.0) and for the yoga versus no treatment group -1.1 (-1.8, -0.4). (iv) More than 50% reduction in seizure duration was found in seven of the 10 patients treated with yoga, compared to none among the 22 controls. The OR (95%CI) for yoga versus sham yoga group was 45 (2.0, 1006.8) and for yoga versus no treatment group 53.57 (2.4, 1187.3). REVIEWER'S CONCLUSIONS: No reliable conclusions can be drawn regarding the efficacy of yoga as a treatment for epilepsy. Further studies are necessary to evaluate the efficacy of yoga in the treatment of epilepsy.
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Yoga for epilepsy.
Ramaratnam S, Sridharan K.
Department of Neurology, Apollo Hospitals, 21 Greams Lane, Off Greams Road, Madras, Tamil Nadu, India, 600006. rsridharan@vsnl.com
BACKGROUND: Stress is considered an important precipitating factor for seizures. Yoga is believed to induce relaxation and stress reduction. The effect of yoga on the EEG and the autonomic nervous system have been reported. Yoga would be an attractive therapeutic option for epilepsy (if proved effective), in view of its nonpharmacological nature, minimal side effects and international acceptance. OBJECTIVES: To assess the efficacy of yoga in the treatment of patients with epilepsy. SEARCH STRATEGY: We searched the Cochrane Epilepsy Group trial register, the Cochrane Controlled Trials Register (The Cochrane Library Issue 4, 1998), MEDLINE for articles published up to the middle of 1998, and also registries of the research council for complimentary medicine were searched. In addition, we searched the references of all the identified studies. Finally, we contacted the members of the Neurological Society of India, several neurophysiology institutions and yoga institutes to seek any ongoing studies or studies published in nonindexed journals or unpublished studies. SELECTION CRITERIA: Randomized control trials and controlled clinical trials of treatment of epilepsy with yoga. DATA COLLECTION AND ANALYSIS: The data were extracted independently by both reviewers and any discrepancies were resolved by discussion. The main outcomes assessed were percentage of patients rendered seizure free, number of patients with more than 50% reduction in seizure frequency or seizure duration and the overall reduction in seizure frequency. Analyses were on an intention to treat basis. MAIN RESULTS: Only one study met the selection criteria, and recruited a total of 32 patients, 10 to sahaja yoga and 22 to control treatments. Antiepileptic drugs were continued in all. Randomization was by roll of a dice. The results of this study are as follows: (i) Four patients treated with yoga were seizure free for six months compared to none in the control groups. The Odds Ratio (OR) (95% Confidence Interval (CI)) for yoga versus sham yoga group was 14.5 (0.7, 316.7) and for yoga versus no treatment group 17.3 (0.8, 373.5). (ii) Nine patients in the yoga group had more than 50% reduction in seizure frequency compared to only one among the controls. The OR (95% CI) for yoga versus sham yoga group was 81 (4.4, 1504.5) and for the yoga versus no treatment group was 158.3 (5.8, 4335.9). (iii) There was a decline in the average number of attacks per month compared to the baseline frequency among the patients treated with yoga. The weighted mean difference ( 95% CI) between yoga versus sham yoga group was -
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Hum Brain Mapp 1999;7(2):98-105
A 15O-H2O PET study of meditation and the resting state of normal consciousness.
Lou HC, Kjaer TW, Friberg L, Wildschiodtz G, Holm S, Nowak M.
Kennedy Institute, Glostrup, Denmark. hcl@kennedy.dk
The aim of the present study was to examine whether the neural structures subserving meditation can be reproducibly measured, and, if so, whether they are different from those supporting the resting state of normal consciousness. Cerebral blood flow distribution was investigated with the 15O-H20 PET technique in nine young adults, who were highly experienced yoga teachers, during the relaxation meditation (Yoga Nidra), and during the resting state of normal consciousness. In addition, global CBF was measured in two of the subjects. Spectral EEG analysis was performed throughout the investigations. In meditation, differential activity was seen, with the noticeable exception of V1, in the posterior sensory and associative cortices known to participate in imagery tasks. In the resting state of normal consciousness (compared with meditation as a baseline), differential activity was found in dorso-lateral and orbital frontal cortex, anterior cingulate gyri, left temporal gyri, left inferior parietal lobule, striatal and thalamic regions, pons and cerebellar vermis and hemispheres, structures thought to support an executive attentional network. The mean global flow remained unchanged for both subjects throughout the investigation (39+/-5 and 38+/-4 ml/100 g/min, uncorrected for partial volume effects). It is concluded that the (H2)15O PET method may measure CBF distribution in the meditative state as well as during the resting state of normal consciousness, and that characteristic patterns of neural activity support each state. These findings enhance our understanding of the neural basis of different aspects of consciousness.
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Lou HC, Kjaer TW, Friberg L, Wildschiodtz G, Holm S, Nowak M.
Kennedy Institute, Glostrup, Denmark. hcl@kennedy.dk
The aim of the present study was to examine whether the neural structures subserving meditation can be reproducibly measured, and, if so, whether they are different from those supporting the resting state of normal consciousness. Cerebral blood flow distribution was investigated with the 15O-
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Indian J Physiol Pharmacol 1997 Apr;41(2):179-82
A combination of focusing and defocusing through yoga reduces optical illusion more than focusing alone.
Telles S, Nagarathna R, Vani PR, Nagendra HR.
Vivekananda Kendra Yoga Research Foundation, Bangalore.
The degree of optical illusion was assessed using standard Muller-Lyer lines in two groups (yoga and control) of thirty subjects each. All subjects were between eighteen and forty two years of age. The difference between the reading at which the lines were actually equal and the reading at which the subject felt them to be equal, was noted as the degree of illusion ("di"). Each subject was assessed at the beginning and end of a month. During the month the yoga group received training in yoga, while the control group carried on with their usual routine. At the end of the month the yoga group showed a significant (two factor ANOVA, Tukey test, P < .001) decrease in the "di" (86%), whereas the control group showed no change. The improvement following yoga could be attributed to the combination of focusing and defocusing involved in yoga practice, as these factors are known to influence the "di". Previous results which mentioned a 79% decrease in "di" with focusing alone, provided a comparison.
Telles S, Nagarathna R, Vani PR, Nagendra HR.
Vivekananda Kendra Yoga Research Foundation, Bangalore.
The degree of optical illusion was assessed using standard Muller-
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Indian J Physiol Pharmacol 1997 Jan;41(1):71-4
Progressive increase in critical flicker fusion frequency following yoga training.
Vani PR, Nagarathna R, Nagendra HR, Telles S.
Vivekananda Kendra Yoga Research Foundation, K. G. Nagar, Bangalore.
The critical flicker fusion frequency (CFF) is the frequency at which a flickering stimulus is perceived to be steady, with higher values suggesting greater perceptual accuracy. The CFF was measured in two age-matched groups of healthy male volunteers whose ages ranged from 25 to 39 years, with 18 subjects in each group. After baseline assessments one group (yoga group) received yoga training, while the other group (control group) carried on with their routine activities. Yoga practices included asanas, pranayamas, kriyas, meditation, devotional sessions and lectures on the theory of yoga. After 10 days neither group showed a change in CFF. However, at 20 and at 30 days the yoga group showed significant increases in CFF by 11.1% and 14.9%, respectively (two factor ANOVA, Tukey multiple comparison test). The control group showed no change at the day 20 and day 30 followup.
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Vani PR, Nagarathna R, Nagendra HR, Telles S.
Vivekananda Kendra Yoga Research Foundation, K. G. Nagar, Bangalore.
The critical flicker fusion frequency (CFF) is the frequency at which a flickering stimulus is perceived to be steady, with higher values suggesting greater perceptual accuracy. The CFF was measured in two age-
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Indian J Med Res 1996 Mar;103:165-72
Effect of Sahaja yoga practice on seizure control & EEG changes in patients of epilepsy.
Panjwani U, Selvamurthy W, Singh SH, Gupta HL, Thakur L, Rai UC.
Defence Institute of Physiology & Allied Sciences, New Delhi.
The effect of Sahaja yoga meditation on seizure control and electroencephalographic alterations was assessed in 32 patients of idiopathic epilepsy. The subjects were randomly divided into 3 groups. Group I (n = 10) practised Sahaja yoga for 6 months, Group II (n = 10) practised exercises mimicking Sahaja yoga for 6 months and Group III (n = 12) served as the epileptic control group. Group I subjects reported a 62 per cent decrease in seizure frequency at 3 months and a further decrease of 86 per cent at 6 months of intervention. Power spectral analysis of EEG showed a shift in frequency from 0-8 Hz towards 8-20 Hz. The ratios of EEG powers in delta (D), theta (T), alpha (A) and beta (B) bands i.e., A/D, A/D + T, A/T and A + B/D + T were increased. Per cent D power decreased and per cent A increased. No significant changes in any of the parameters were found in Groups II and III, indicating that Sahaja yoga practice brings about seizure reduction and EEG changes. Sahaja yoga could prove to be beneficial in the management of patients of epilepsy.
Panjwani U, Selvamurthy W, Singh SH, Gupta HL, Thakur L, Rai UC.
Defence Institute of Physiology & Allied Sciences, New Delhi.
The effect of Sahaja yoga meditation on seizure control and electroencephalographic alterations was assessed in 32 patients of idiopathic epilepsy. The subjects were randomly divided into 3 groups. Group I (n = 10) practised Sahaja yoga for 6 months, Group II (n = 10) practised exercises mimicking Sahaja yoga for 6 months and Group III (n = 12) served as the epileptic control group. Group I subjects reported a 62 per cent decrease in seizure frequency at 3 months and a further decrease of 86 per cent at 6 months of intervention. Power spectral analysis of EEG showed a shift in frequency from 0-
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Psychiatry Clin Neurosci 1995 May;49(2):107-10
The fourth state of consciousness: the Thuriya Avastha.
Ramamurthi B.
Neurosurgical Centre, Voluntary Health Services, Madras, India.
Present day neurophysiology stops with attributing thinking processes as the highest level of function of the brain. It has been common knowledge to oriental thinkers for many centuries, that there are many further states of the human mind, culminating in the state of thoughtless awareness; the fourth state of consciousness. This state must have a physiological basis. The complicated structure of the brain, the extravagant abundance of neural and glial elements in the brain, the infinite possibilities of synaptic junctions and synaptic transmission, and the multitude of neurotransmitters and neuromodulators; all these point to the definite possibility of a much greater level of performance and achievement for the human brain than has been apparent so far. Not only the theories but also the experience of Eastern seers have shown that the brain can transcend the boundaries of logic and reason, and experience states of awareness, commonly unrecognized. In the past few decades, knowledge about the functioning of the human brain has been growing exponentially and scientists of diverse disciplines are concentrating on unraveling its mysteries. It is necessary for scientists to investigate this state with all available tools and find the neurophysiological basis of this state.
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Ramamurthi B.
Neurosurgical Centre, Voluntary Health Services, Madras, India.
Present day neurophysiology stops with attributing thinking processes as the highest level of function of the brain. It has been common knowledge to oriental thinkers for many centuries, that there are many further states of the human mind, culminating in the state of thoughtless awareness; the fourth state of consciousness. This state must have a physiological basis. The complicated structure of the brain, the extravagant abundance of neural and glial elements in the brain, the infinite possibilities of synaptic junctions and synaptic transmission, and the multitude of neurotransmitters and neuromodulators; all these point to the definite possibility of a much greater level of performance and achievement for the human brain than has been apparent so far. Not only the theories but also the experience of Eastern seers have shown that the brain can transcend the boundaries of logic and reason, and experience states of awareness, commonly unrecognized. In the past few decades, knowledge about the functioning of the human brain has been growing exponentially and scientists of diverse disciplines are concentrating on unraveling its mysteries. It is necessary for scientists to investigate this state with all available tools and find the neurophysiological basis of this state.
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Indian J Physiol Pharmacol 1995 Apr;39(2):111-6
Effect of Sahaja yoga practice on stress management in patients of epilepsy.
Panjwani U, Gupta HL, Singh SH, Selvamurthy W, Rai UC.
Defence Institute of Physiology and Allied Sciences, Delhi.
An attempt was made to evaluate the effect of Sahaja yoga meditation in stress management in patients of epilepsy. The study was carried out on 32 patients of epilepsy who were rendomly divided into 3 groups: group I subjects practised Sahaja yoga meditation for 6 months, group II subjects practised postural exercises mimicking Sahaja yoga and group III served as the epileptic control group. Galvanic skin resistance (GSR), blood lactate and urinary vinyl mandelic acid (U-VMA) were recorded at 0, 3 and 6 months. There were significant changes at 3 & 6 months as compared to 0 month values in GSR, blood lactate and U-VMA levels in group I subjects, but not in group II and group III subjects. The results indicate that reduction in stress following Sahaja yoga practice may be responsible for clinical improvement which had been earlier reported in patients who practised Sahaja yoga.
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Panjwani U, Gupta HL, Singh SH, Selvamurthy W, Rai UC.
Defence Institute of Physiology and Allied Sciences, Delhi.
An attempt was made to evaluate the effect of Sahaja yoga meditation in stress management in patients of epilepsy. The study was carried out on 32 patients of epilepsy who were rendomly divided into 3 groups: group I subjects practised Sahaja yoga meditation for 6 months, group II subjects practised postural exercises mimicking Sahaja yoga and group III served as the epileptic control group. Galvanic skin resistance (GSR), blood lactate and urinary vinyl mandelic acid (U-
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Int J Psychophysiol 1994 Oct;18(1):75-9
EEG changes during forced alternate nostril breathing.
Stancak A Jr, Kuna M.
Department of Physiology and Clinical Physiology, Charles IV University, Prague, Czech Republic.
The effects of 10 min forced alternate nostril breathing (FANB) on EEG topography were studied in 18 trained subjects. One type of FANB consisted in left nostril inspiration and right nostril expiration and the other type in right nostril inspiration and left nostril expiration. Mean power in the beta bands and partially in the alpha band increased during FANB irrespective of the type of nostril breathing. In addition, hemisphere asymmetry in the beta 1 band decreased in the second half of FANB suggesting that FANB has a balancing effect on the functional activity of the left and right hemisphere.
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Stancak A Jr, Kuna M.
Department of Physiology and Clinical Physiology, Charles IV University, Prague, Czech Republic.
The effects of 10 min forced alternate nostril breathing (FANB) on EEG topography were studied in 18 trained subjects. One type of FANB consisted in left nostril inspiration and right nostril expiration and the other type in right nostril inspiration and left nostril expiration. Mean power in the beta bands and partially in the alpha band increased during FANB irrespective of the type of nostril breathing. In addition, hemisphere asymmetry in the beta 1 band decreased in the second half of FANB suggesting that FANB has a balancing effect on the functional activity of the left and right hemisphere.
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Nurs Times 1994 Jul 20-26;90(29):35-6
Acute and prophylactic treatment of migraine.
Reilly R.
Migraine affects one in 10 adults and is a debilitating condition. The symptoms and pathogenesis of migraine are discussed, including known triggers. Acute and prophylactic treatments currently available are described, as are alternative treatments such as acupuncture and yoga.
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Reilly R.
Migraine affects one in 10 adults and is a debilitating condition. The symptoms and pathogenesis of migraine are discussed, including known triggers. Acute and prophylactic treatments currently available are described, as are alternative treatments such as acupuncture and yoga.
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Int J Neurosci 1993 Nov;73(1-2):61-8
The effects of unilateral forced nostril breathing on cognitive performance.
Jella SA, Shannahoff-Khalsa DS.
Department of Psychiatry University of California, Davis 95817.
This study describes the effects of 30 minutes of unilateral forced nostril breathing on cognitive performance in 51 right-handed undergraduate psychology students (25 males and 26 females). A verbal analogies task modeled after the Miller Analogies and SAT Tests was used as a test of left-hemispheric performance and mental rotation tasks based on the Vandenburg and Kuse adaptation of Shepard and Metzler's tests were used as spatial tasks for testing right-hemispheric performance. Spatial task performance was significantly enhanced during left nostril breathing in both males and females, p = .028. Verbal task performance was greater during right nostril breathing, but not significantly p = .14. These results are discussed in comparison to other cognitive and physiological studies using unilateral forced nostril breathing. This yogic breathing technique may have useful application in treating psychophysiological disorders with hemispheric imbalances and disorders with autonomic abnormalities.
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Jella SA, Shannahoff-
Department of Psychiatry University of California, Davis 95817.
This study describes the effects of 30 minutes of unilateral forced nostril breathing on cognitive performance in 51 right-
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Int J Psychophysiol 1993 Sep;15(2):147-52
Autonomic changes in Brahmakumaris Raja yoga meditation.
Telles S, Desiraju T.
Department of Neurophysiology, National Institute of Mental Health and Neurosciences, Bangalore, India.
This report presents the changes in various autonomic and respiratory variables during the practice of Brahmakumaris Raja yoga meditation. This practice requires considerable commitment and involves concentrated thinking. 18 males in the age range of 20 to 52 years (mean 34.1 +/- 8.1), with 5-25 years experience in mediation (mean 10.1 +/- 6.2), participated in the study. Each subject was assessed in three test sessions which included a period of meditation, and also in three control (non-mediation) sessions, which included a period of random thinking. Group analysis showed that the heart rate during the meditation period was increased compared to the preceding baseline period, as well as compared to the value during the non-meditation period of control sessions. In contrast to the change in the heart rate, there was no significant change during meditation, for the group as a whole, in palmar GSR, finger plethysmogram amplitude, and respiratory rate. On an individual basis, changes which met the following criteria were noted: (1), changes which were greater during meditation (compared to its preceding baseline) than changes during post meditation or non-meditation periods (also compared to their preceding baseline); (2), Changes which occurred consistently during the three repeat sessions of a subject and (3), changes which exceeded arbitrarily-chosen cut-off points (described at length below). This individual level analysis revealed that changes in autonomic variables suggestive of both activation and relaxation occurred simultaneously in different subdivisions of the autonomic nervous system in a subject. Apart from this, there were differences in patterns of change among the subjects who practised the same meditation.
Telles S, Desiraju T.
Department of Neurophysiology, National Institute of Mental Health and Neurosciences, Bangalore, India.
This report presents the changes in various autonomic and respiratory variables during the practice of Brahmakumaris Raja yoga meditation. This practice requires considerable commitment and involves concentrated thinking. 18 males in the age range of 20 to 52 years (mean 34.1 +/-
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Int J Psychophysiol 1993 May;14(3):189-98
Alterations of auditory middle latency evoked potentials during yogic consciously regulated breathing and attentive state of mind.
Telles S, Joseph C, Venkatesh S, Desiraju T.
Department of Neurophysiology, National Institute of Mental Health and Neuro Sciences, Bangalore, India.
Middle latency auditory-evoked potentials (AEP-MLRs) of 10 healthy male subjects in the age range of 21-33 years, were assessed to determine whether yogic pranayamic practice would cause changes in them. The pranayama type assessed here is an exercise of consciously-controlled rhythmic breathing involving timed breath-holding in each cycle of breathing, while the subject holds utmost attention and experiences the touch of inhaled air in the nasal passage. The results revealed that the Na-wave amplitude increased and latency decreased during the period of pranayamic practice, whereas the Pa-wave was not significantly altered. The change is interpreted as an indication of a generalized alteration cause in information processing at the primary thalamo-cortical level during the concentrated mental exercise of inducing modifications in neural mechanisms regulating a different functional system (respiratory). Further researches are required to understand the operational significances of such changes.
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Telles S, Joseph C, Venkatesh S, Desiraju T.
Department of Neurophysiology, National Institute of Mental Health and Neuro Sciences, Bangalore, India.
Middle latency auditory-
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Homeost Health Dis 1991 Dec;33(4):182-9
Kapalabhati--yogic cleansing exercise. II. EEG topography analysis.
Stancak A Jr, Kuna M, Srinivasan, Dostalek C, Vishnudevananda S.
Institute of Physiological Regulations, Czechoslovak Academy of Sciences, Praha.
Topography of brain electrical activity was studied in 11 advanced yoga practitioners during yogic high-frequency breathing kapalabhati (KB). Alpha activity was increased during the initial five min of KB. Theta activity mostly in the occipital region was increased during later stages of 15 min KB compared to the pre-exercise period. Beta 1 activity increased during the first 10 min of KB in occipital and to a lesser degree in parietal regions. Alpha and beta 1 activity decreased and theta activity was maintained on the level of the initial resting period after KB. The score of General Deactivation factor from Activation Deactivation Adjective Checklist was higher after KB exercise than before the exercise. The results suggest a relative increase of slower EEG frequencies and relaxation on a subjective level as the after effect of KB exercise.
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Stancak A Jr, Kuna M, Srinivasan, Dostalek C, Vishnudevananda S.
Institute of Physiological Regulations, Czechoslovak Academy of Sciences, Praha.
Topography of brain electrical activity was studied in 11 advanced yoga practitioners during yogic high-
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Neuropsychobiology 1990-91;23(4):182-7
Changed pattern of regional glucose metabolism during yoga meditative relaxation.
Herzog H, Lele VR, Kuwert T, Langen KJ, Kops ER, Feinendegen LE.
Institute of Medicine, Research Center Julich, FRG.
Using positron emission tomography (PET), measurements of the regional cerebral metabolic rate of glucose (rCMRGlc) are able to delineate cerebral metabolic responses to external or mental stimulation. In order to examine possible changes of brain metabolism due to Yoga meditation PET scans were performed in 8 members of a Yoga meditation group during the normal control state (C) and Yoga meditative relaxation (YMR). Whereas there were intraindividual changes of the total CMRGlc, the alterations were not significant for intergroup comparison; specific focal changes or changes in the interhemispheric differences in metabolism were also not seen; however the ratios of frontal vs. occipital rCMRGlc were significantly elevated (p less than 0.05) during YMR. These altered ratios were caused by a slight increase of frontal rCMRGlc and a more pronounced reduction in primary and secondary visual centers. These data indicate a holostic behavior of the brain metabolism during the time of altered state of consciousness during YMR.
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Herzog H, Lele VR, Kuwert T, Langen KJ, Kops ER, Feinendegen LE.
Institute of Medicine, Research Center Julich, FRG.
Using positron emission tomography (PET), measurements of the regional cerebral metabolic rate of glucose (rCMRGlc) are able to delineate cerebral metabolic responses to external or mental stimulation. In order to examine possible changes of brain metabolism due to Yoga meditation PET scans were performed in 8 members of a Yoga meditation group during the normal control state (C) and Yoga meditative relaxation (YMR). Whereas there were intraindividual changes of the total CMRGlc, the alterations were not significant for intergroup comparison; specific focal changes or changes in the interhemispheric differences in metabolism were also not seen; however the ratios of frontal vs. occipital rCMRGlc were significantly elevated (p less than 0.05) during YMR. These altered ratios were caused by a slight increase of frontal rCMRGlc and a more pronounced reduction in primary and secondary visual centers. These data indicate a holostic behavior of the brain metabolism during the time of altered state of consciousness during YMR.
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Act Nerv Super (Praha) 1985 Jun;27(2):81-8
EEG patterns suggestive of shifted levels of excitation effected by hathayogic exercises.
Roldan E, Dostalek C.
Concurrent with the performance of hathayogic exercises such as Nauli, Bhastrika and Suryabhedana, three characteristic EEG patterns were identified: a "wicket" rhythm at a frequency wave of 12 to 17 Hz, recordable from para-Rolandic areas, which we have called Xi rhythm; a 26-33 Hz sinusoidal activity, confined to the mid-sagittal parietooccipital region; and paroxysmal activity localized in the lateral boundaries of parieto-temporo-occipital regions, bilaterally. - The expectation that hathayogic exercises would affect the electrical activity of circumscribed, relatively well defined areas of the brain was based on the fact that these exercises imply a strong stimulation of somatic and splanchnic receptors, the afferent impulses of which are fed into specific cortical representation areas localized for the most part around central and anterior parietal areas.
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Roldan E, Dostalek C.
Concurrent with the performance of hathayogic exercises such as Nauli, Bhastrika and Suryabhedana, three characteristic EEG patterns were identified: a "wicket" rhythm at a frequency wave of 12 to 17 Hz, recordable from para-
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Arch Gen Psychiatry 1978 May;35(5):571-7
Psychophysiological correlates of the practice of Tantric Yoga meditation.
Corby JC, Roth WT, Zarcone VP Jr, Kopell BS.
Autonomic and electroencephalographic (EEG) correlates of Tantric Yoga meditation were studied in three groups of subjects as they progressed from normal consciousness into meditation. Groups differed in their level of meditation proficiency. Measures of skin resistance, heart rate, respiration, autonomic orienting responses, resting EEG, EEG alpha and theta frequencies, sleep-scored EEG, averaged evoked responses, and subjective experience were employed. Unlike most previously reported meditation studies, proficient meditators demonstrated increased autonomic activation during meditation while unexperienced meditators demonstrated autonomic relaxation. During meditation, proficient meditators demonstrated increased alpha and theta power, minimal evidence of EEG-defined sleep, and decreased autonomic orienting to external stimulation. An episode of sudden autonomic activation was observed that was characterized by the meditator as an approach to the Yogic ecstatic state of intense concentration. These findings challenge the current "relaxation" model of meditative states.
Corby JC, Roth WT, Zarcone VP Jr, Kopell BS.
Autonomic and electroencephalographic (EEG) correlates of Tantric Yoga meditation were studied in three groups of subjects as they progressed from normal consciousness into meditation. Groups differed in their level of meditation proficiency. Measures of skin resistance, heart rate, respiration, autonomic orienting responses, resting EEG, EEG alpha and theta frequencies, sleep-
